Measuring Quality-Adjusted Life-Years When Health Fluctuates

Measuring health-related quality of life (HRQoL) and quality-adjusted life years (QALY) in the critical care setting

Investing when Volatility Fluctuates∗

We examine how the evidence of the time-varying volatility in stock returns affects optimal dynamic portfolio choice of investors with long horizons. As return volatility shows a relatively small correlation with realized return, its time-variation is expected to cause little, if any, hedging demand (in the sense of Merton (1973)). However, we find that, once transaction costs are taken into ac...

Burden of Disease in Asian Countries and the use of Disability-Adjusted Life-Years and Quality-Adjusted Life-Years.

• Both QALYs and DALYs are also usually discounted, meaning more weight can be given to immediate over distant outcomes, and both measures can account for disease severity. The two measures however are not interchangeable.1 For example, DALYs incorporate an age-weighting function, which assigns lower weights to the years of the young and elderly, and the origins of disability and quality of lif...

Problems and solutions in calculating quality-adjusted life years (QALYs)

The quality-adjusted life-year (QALY) is a measure of the value of health outcomes. Since health is a function of length of life and quality of life, the QALY was developed as an attempt to combine the value of these attributes into a single index number. The QALY calculation is simple: the change in utility value induced by the treatment is multiplied by the duration of the treatment effect to...

Utility and quality-adjusted life-years in coronary artery disease

OBJECTIVES This study evaluated the utility and quality-of-life year measurements for patients with coronary artery disease who underwent any of 3 therapeutic strategies with a 5-year follow-up. METHODS Quality-of-life data were obtained from the Medicine, Angioplasty, or Surgery Study II trial. To obtain utilities, the 36-Item Short-Form questionnaire was converted to a 6-Dimensional Health ...